Version 5.4
Homo sapiens Gene: PLCL2
Summary
InnateDB Gene IDBG-21444.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLCL2
Gene Name phospholipase C-like 2
Synonyms PLCE2
Species Homo sapiens
Ensembl Gene ENSG00000154822
Encoded Proteins
IDBP-366868
phospholipase C-like 2
IDBP-366871
phospholipase C-like 2
IDBP-810163
phospholipase C-like 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:16802651-17090594
Strand Forward strand
Band p24.3
Transcripts
ENST00000432376 ENSP00000412836
ENST00000419842 ENSP00000404433
ENST00000460467
ENST00000615277 ENSP00000478458
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004435 phosphatidylinositol phospholipase C activity
GO:0004871 signal transducer activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0008081 phosphoric diester hydrolase activity
GO:0050811 GABA receptor binding
Biological Process
GO:0002322 B cell proliferation involved in immune response
GO:0002337 B-1a B cell differentiation
GO:0006629 lipid metabolic process
GO:0007165 signal transduction
GO:0007214 gamma-aminobutyric acid signaling pathway
GO:0032228 regulation of synaptic transmission, GABAergic
GO:0033135 regulation of peptidyl-serine phosphorylation
GO:0035556 intracellular signal transduction
GO:0050859 negative regulation of B cell receptor signaling pathway
GO:1900122 positive regulation of receptor binding
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000038910
View Gene Order
ENSBTAG00000009942
Not yet available
Cross-References
SwissProt Q9UPR0
TrEMBL
UniProt Splice Variant
Entrez Gene 23228
UniGene Hs.202010 Hs.598760 Hs.741267
RefSeq NM_015184 NM_001144382 XM_006713073
HUGO HGNC:9064
OMIM 614276
CCDS CCDS33713 CCDS74911
HPRD 07147
IMGT
EMBL AB029015 AK023546 AK291419 AL117515 BC036392
GenPept AAH36392 BAA83044 BAB14606 BAF84108 CAB55974
RNA Seq Atlas 23228

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca