Version 5.4
Mus musculus Gene: Plcl2
Summary
InnateDB Gene IDBG-190434.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Plcl2
Gene Name phospholipase C-like 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000038910
Encoded Proteins
IDBP-190436
phospholipase C-like 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000154822:
Gene Information
Type Protein coding
Genomic Location Chromosome 17:50509547-50688493
Strand Forward strand
Band C
Transcripts
ENSMUST00000043938 ENSMUSP00000046584
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004435 phosphatidylinositol phospholipase C activity
GO:0004871 signal transducer activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0008081 phosphoric diester hydrolase activity
GO:0050811 GABA receptor binding
Biological Process
GO:0002322 B cell proliferation involved in immune response
GO:0002337 B-1a B cell differentiation
GO:0006629 lipid metabolic process
GO:0007165 signal transduction
GO:0007214 gamma-aminobutyric acid signaling pathway
GO:0032228 regulation of synaptic transmission, GABAergic
GO:0033135 regulation of peptidyl-serine phosphorylation
GO:0035556 intracellular signal transduction
GO:0050859 negative regulation of B cell receptor signaling pathway
GO:1900122 positive regulation of receptor binding
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000154822
View Gene Order
ENSBTAG00000009942
Not yet available
Cross-References
SwissProt Q8K394
TrEMBL
UniProt Splice Variant
Entrez Gene 224860
UniGene
RefSeq NM_013880 XM_006524150 XM_006524151 XM_006524152
OMIM
CCDS CCDS28875
HPRD
IMGT
MGI ID MGI:1352756
MGI Symbol Plcl2
EMBL AB033615 AK122439 AK154288 BC027746
GenPept AAH27746 BAA89457 BAC65721 BAE32490
RNA Seq Atlas 224860

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca