Version 5.4
Mus musculus Gene: Scube1
Summary
InnateDB Gene IDBG-168528.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Scube1
Gene Name signal peptide, CUB domain, EGF-like 1
Synonyms 7330410C13Rik; A630023E24Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000016763
Encoded Proteins
IDBP-168530
signal peptide, CUB domain, EGF-like 1
IDBP-168532
signal peptide, CUB domain, EGF-like 1
IDBP-168534
signal peptide, CUB domain, EGF-like 1
IDBP-623534
signal peptide, CUB domain, EGF-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000159307:
This gene encodes a cell surface glycoprotein that is a member of the SCUBE (signal peptide, CUB domain, EGF (epidermal growth factor)-like protein) family. Family members have an amino-terminal signal peptide, nine copies of EGF-like repeats and a CUB domain at the carboxyl terminus. This protein is expressed in platelets and endothelial cells and may play an important role in vascular biology. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:83602583-83725021
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000043634 ENSMUSP00000044835
ENSMUST00000016907 ENSMUSP00000016907
ENSMUST00000076060 ENSMUSP00000075434
ENSMUST00000144773
ENSMUST00000171496 ENSMUSP00000130131
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0051260 protein homooligomerization
Cellular Component
GO:0005615 extracellular space
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0019897 extrinsic component of plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000159307
View Gene Order
ENSBTAG00000011275
Not yet available
Cross-References
SwissProt
TrEMBL Q68EF9
UniProt Splice Variant
Entrez Gene 64706
UniGene Mm.40393
RefSeq NM_001271473 NM_001271472 NM_022723
OMIM
CCDS CCDS70654 CCDS49684 CCDS70655
HPRD
IMGT
MGI ID MGI:1890616
MGI Symbol Scube1
EMBL AL583887 AL591964 BC080278
GenPept AAH80278
RNA Seq Atlas 64706

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca