InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rab11a

Summary

InnateDB Protein

IDBP-621263.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rab11a

Protein Name

RAB11a, member RAS oncogene family

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000129729

InnateDB Gene

IDBG-176597 (Rab11a)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 49 interaction(s) predicted by orthology.

Experimentally validated
Total	12 [view]
Protein-Protein	12 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	49 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005515	protein binding
GO:0005525	GTP binding

Biological Process

GO:0006184	GTP catabolic process
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction
GO:0015031	protein transport
GO:0045773	positive regulation of axon extension

Cellular Component

GO:0005622	intracellular
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005802	trans-Golgi network
GO:0016020	membrane
GO:0030424	axon
GO:0048471	perinuclear region of cytoplasm
GO:0055037	recycling endosome

Protein Structure and Domains

PDB ID

MGI:1858202

InterPro

IPR000795 Elongation factor, GTP-binding domain
IPR001806 Small GTPase superfamily
IPR003578 Small GTPase superfamily, Rho type
IPR003579 Small GTPase superfamily, Rab type
IPR005225 Small GTP-binding protein domain
IPR006689 Small GTPase superfamily, ARF/SAR type
IPR013684 Mitochondrial Rho-like
IPR020849 Small GTPase superfamily, Ras type
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00009
PF00071
PF00025
PF08477

PRINTS

PR00315
PR00449
PR00328

PIRSF

SMART

SM00174
SM00175
SM00173

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E9Q3P9

UniProt Splice Variant

Entrez Gene

53869

UniGene

Mm.474718

RefSeq

MGI ID

MGI Symbol

Rab11a

OMIM

CCDS

HPRD

IMGT

EMBL

AC147560

GenPept