InnateDB Protein
|
IDBP-597497.2
|
Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TRAF3
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Protein Name
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TNF receptor-associated factor 3
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Synonyms
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CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000453623
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InnateDB Gene
|
IDBG-21240 (TRAF3)
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Protein Structure
|
|
Function |
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 195 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.
Experimentally validated |
Total |
195
[view]
|
Protein-Protein |
192
[view]
|
Protein-DNA |
1
[view]
|
Protein-RNA |
0
|
DNA-DNA |
2
[view]
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
27 [view]
|
|
|
Molecular Function |
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Biological Process |
GO:0008063
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Toll signaling pathway
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GO:0032088
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negative regulation of NF-kappaB transcription factor activity
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GO:0033209
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tumor necrosis factor-mediated signaling pathway
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GO:0045087
|
innate immune response (InnateDB)
|
GO:0050688
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regulation of defense response to virus
|
|
Cellular Component |
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PDB ID |
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InterPro |
IPR001841
Zinc finger, RING-type
|
PFAM |
PF13639
PF14634
|
PRINTS |
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PIRSF |
|
SMART |
SM00184
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TIGRFAMs |
|
Modification |
|
SwissProt |
|
PhosphoSite |
PhosphoSite-
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TrEMBL |
H0YMI8
|
UniProt Splice Variant |
|
Entrez Gene |
7187
|
UniGene |
Hs.732634
|
RefSeq |
|
HUGO |
HGNC:12033
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OMIM |
601896
|
CCDS |
|
HPRD |
03539
|
IMGT |
|
EMBL |
AL117209
AL132801
|
GenPept |
|
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