Homo sapiens Gene: UBXN6
Summary
InnateDB Gene IDBG-18959.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UBXN6
Gene Name UBX domain protein 6
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000167671
Encoded Proteins
UBX domain protein 6
UBX domain protein 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:4444999-4457822
Strand Reverse strand
Band p13.3
Transcripts
ENST00000301281 ENSP00000301281
ENST00000394765 ENSP00000378246
ENST00000592515 ENSP00000464967
ENST00000592358
ENST00000593024
ENST00000590466 ENSP00000466148
ENST00000588238
ENST00000587009
ENST00000591919 ENSP00000467206
ENST00000587324
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 48 experimentally validated interaction(s) in this database.
Experimentally validated
Total 48 [view]
Protein-Protein 48 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005815 microtubule organizing center
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL K7ELN1
UniProt Splice Variant
Entrez Gene 80700
UniGene Hs.435255 Hs.609016
RefSeq NM_001171091 NM_025241
HUGO HGNC:14928
OMIM 611946
CCDS CCDS12129 CCDS54201
HPRD 18253
IMGT
EMBL AC011498
GenPept
RNA Seq Atlas 100616371 80700