InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: RAB11A

Summary

InnateDB Gene

IDBG-645409.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RAB11A

Gene Name

ras-related protein Rab-11A

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000018959

Encoded Proteins

IDBP-698113

ras-related protein Rab-11A

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

InnateDB Annotation from Orthologs

Summary

PMID 20933442

[Homo sapiens] RAB11A is an important regulator of Toll-like receptor 4 (TLR4) and TRAM transport to E. coli phagosomes thereby controlling IRF3 activation from this compartment.

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000103769:
The protein encoded by this gene belongs to the Rab family of the small GTPase superfamily. It is associated with both constitutive and regulated secretory pathways, and may be involved in protein transport. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 10:12691046-12710296

Strand

Forward strand

Band

Transcripts

ENSBTAT00000025235

ENSBTAP00000025235

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 51 interaction(s) predicted by orthology.

Predicted by orthology
Total	51 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003924	GTPase activity
GO:0005515	protein binding
GO:0005525	GTP binding

Biological Process

GO:0000910	cytokinesis
GO:0006184	GTP catabolic process
GO:0006886	intracellular protein transport
GO:0006913	nucleocytoplasmic transport
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction
GO:0015031	protein transport
GO:0016192	vesicle-mediated transport
GO:0031175	neuron projection development
GO:0032402	melanosome transport
GO:0045773	positive regulation of axon extension
GO:0072659	protein localization to plasma membrane

Cellular Component

GO:0005622	intracellular
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005802	trans-Golgi network
GO:0016020	membrane
GO:0030424	axon
GO:0032154	cleavage furrow
GO:0043234	protein complex
GO:0045335	phagocytic vesicle
GO:0048471	perinuclear region of cytoplasm
GO:0055037	recycling endosome
GO:0070062	extracellular vesicular exosome