Version 5.4
Mus musculus Gene: Lmcd1
Summary
InnateDB Gene IDBG-174855.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lmcd1
Gene Name LIM and cysteine-rich domains 1
Synonyms AW455500; AW553074; dyxin
Species Mus musculus
Ensembl Gene ENSMUSG00000057604
Encoded Proteins
IDBP-174857
LIM and cysteine-rich domains 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000071282:
The protein encoded by this gene contains a cysteine-rich domain in the N-terminal region and 2 LIM domains in the C-terminal region. It also has several potential phosphorylation and N-myristoylation sites and a single potential N-glycosylation site. The presence of LIM domains implies involvement in protein-protein interactions. Expression of this gene has been detected in most tissues, with highest expression in skeletal muscle. Transcript variants utilizing alternative polyA signals have been observed. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:112273758-112330425
Strand Forward strand
Band E3
Transcripts
ENSMUST00000032376 ENSMUSP00000032376
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003714 transcription corepressor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0010611 regulation of cardiac muscle hypertrophy
GO:0070886 positive regulation of calcineurin-NFAT signaling cascade
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0031012 extracellular matrix
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000071282
View Gene Order
ENSBTAG00000005431
Not yet available
Cross-References
SwissProt Q8VEE1
TrEMBL Q3TVW6
UniProt Splice Variant
Entrez Gene 30937
UniGene Mm.234441 Mm.412715
RefSeq NM_144799 XM_006506225
OMIM
CCDS CCDS20403
HPRD
IMGT
MGI ID MGI:1353635
MGI Symbol Lmcd1
EMBL AK159946 BC019124 CH466523
GenPept AAH19124 BAE35502 EDK99424
RNA Seq Atlas 30937

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca