Version 5.4
Homo sapiens Protein: ZBTB46
Summary
InnateDB Protein IDBP-87319.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZBTB46
Protein Name zinc finger and BTB domain containing 46
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000303102
InnateDB Gene IDBG-87315 (ZBTB46)
Protein Structure
UniProt Annotation
Function Function as a transcriptional repressor for PRDM1. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR000210 BTB/POZ-like
IPR007087 Zinc finger, C2H2
IPR011333 BTB/POZ fold
IPR013069 BTB/POZ
IPR015880 Zinc finger, C2H2-like
IPR021777 Protein of unknown function DUF3342
PFAM PF00096
PF00651
PF11822
PRINTS
PIRSF
SMART SM00225
SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86UZ6
PhosphoSite PhosphoSite-Q86UZ6
TrEMBL
UniProt Splice Variant
Entrez Gene 140685
UniGene Hs.585028
RefSeq XP_006723764
HUGO HGNC:16094
OMIM 614639
CCDS CCDS13538
HPRD 16567
IMGT
EMBL AL121845 BC052269 BC073800 CH471077
GenPept AAH52269 AAH73800 CAI21885 EAW75205 EAW75206

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca