InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ABI1

Summary

InnateDB Protein

IDBP-63989.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ABI1

Protein Name

abl-interactor 1

Synonyms

ABI-1; ABLBP4; E3B1; NAP1BP; SSH3BP; SSH3BP1;

Species

Homo sapiens

Ensembl Protein

ENSP00000279599

InnateDB Gene

IDBG-63979 (ABI1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 80 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.

Experimentally validated
Total	80 [view]
Protein-Protein	80 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	22 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008092	cytoskeletal protein binding
GO:0032403	protein complex binding

Biological Process

GO:0006928	cellular component movement
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
GO:0008154	actin polymerization or depolymerization
GO:0008285	negative regulation of cell proliferation
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0045087	innate immune response

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005829	cytosol
GO:0014069	postsynaptic density
GO:0030027	lamellipodium
GO:0030054	cell junction
GO:0030175	filopodium
GO:0030426	growth cone
GO:0031209	SCAR complex
GO:0045211	postsynaptic membrane
GO:0070062	extracellular vesicular exosome