InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mpv17

Summary

InnateDB Protein

IDBP-251360.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mpv17

Protein Name

MpV17 mitochondrial inner membrane protein

Synonyms

Tg.Mpv17;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000110278

InnateDB Gene

IDBG-488696 (Mpv17)

Protein Structure

UniProt Annotation

Function

Involved in mitochondria homeostasis. May be involved in the metabolism of reactive oxygen species and control of oxidative phosphorylation and mitochondrial DNA (mtDNA) maintenance (Probable). {ECO:0000305PubMed:7957077}.

Subcellular Localization

Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

High levels in heart, kidney, and brain, intermediate levels in testis, and low levels in liver and spleen.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 46 interaction(s) predicted by orthology.

Predicted by orthology
Total	46 [view]

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0000002	mitochondrial genome maintenance
GO:0032836	glomerular basement membrane development
GO:0034614	cellular response to reactive oxygen species
GO:0042592	homeostatic process
GO:0048839	inner ear development
GO:0072593	reactive oxygen species metabolic process
GO:2000377	regulation of reactive oxygen species metabolic process