Version 5.4
Mus musculus Protein: Usp42
Summary
InnateDB Protein IDBP-207859.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Usp42
Protein Name ubiquitin specific peptidase 42
Synonyms 2410140K03Rik; 3110031A07Rik; A630018G05Rik; D5Ertd591e;
Species Mus musculus
Ensembl Protein ENSMUSP00000053955
InnateDB Gene IDBG-207857 (Usp42)
Protein Structure
UniProt Annotation
Function Deubiquitinating enzyme which may play an important role during spermatogenesis. {ECO:0000269PubMed:16904385}.
Subcellular Localization
Disease Associations
Tissue Specificity Highest expression seen in the testis. Also expressed in brain, lung and thymus. The expression level gradually increases from 2 weeks after birth and then decreases from the pachytene spermatocyte (PS) stage during spermatogenesis. {ECO:0000269PubMed:16904385}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 28 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004843 ubiquitin-specific protease activity
GO:0005515 protein binding
GO:0036459 ubiquitinyl hydrolase activity
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007283 spermatogenesis
GO:0016579 protein deubiquitination
GO:0030154 cell differentiation
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:1924050
InterPro IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
IPR028889 Ubiquitin carboxyl-terminal hydrolase-like domain
PFAM PF00443
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt B2RQC2
PhosphoSite PhosphoSite-NP_084025
TrEMBL
UniProt Splice Variant
Entrez Gene 76800
UniGene Mm.473118
RefSeq NP_084025
MGI ID
MGI Symbol Usp42
OMIM
CCDS CCDS39372
HPRD
IMGT
EMBL BC137852 CH466529
GenPept AAI37853 EDL19037

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca