Version 5.4
Homo sapiens Gene: SULT1A2
Summary
InnateDB Gene IDBG-22934.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SULT1A2
Gene Name sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
Synonyms HAST4; P-PST; ST1A2; STP2; TSPST2
Species Homo sapiens
Ensembl Gene ENSG00000197165
Encoded Proteins
IDBP-22936
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
IDBP-239180
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
IDBP-587369
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
IDBP-601431
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
IDBP-598794
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes one of two phenol sulfotransferases with thermostable enzyme activity. Two alternatively spliced variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:28591943-28597109
Strand Reverse strand
Band p11.2
Transcripts
ENST00000335715 ENSP00000338742
ENST00000395630 ENSP00000378992
ENST00000534108 ENSP00000433075
ENST00000533150 ENSP00000435271
ENST00000526384 ENSP00000435358
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004062 aryl sulfotransferase activity
GO:0008146 sulfotransferase activity
GO:0047894 flavonol 3-sulfotransferase activity
Biological Process
GO:0006584 catecholamine metabolic process
GO:0006805 xenobiotic metabolic process
GO:0008152 metabolic process
GO:0008202 steroid metabolic process
GO:0009309 amine biosynthetic process
GO:0018958 phenol-containing compound metabolic process
GO:0044281 small molecule metabolic process
GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process
GO:0051923 sulfation
Cellular Component
GO:0005829 cytosol
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_6913
Cytosolic sulfonation of small molecules pathway
REACT_6959
Phase II conjugation pathway
REACT_111217
Metabolism pathway
REACT_13433
Biological oxidations pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E9PM76
UniProt Splice Variant
Entrez Gene 6799
UniGene Hs.546304
RefSeq NM_001054 NM_177528 XM_006721076 XM_006721077
HUGO HGNC:11454
OMIM 601292
CCDS CCDS10636
HPRD 03187
IMGT
EMBL AC020765
GenPept
RNA Seq Atlas 6799

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca