InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GMFB

Summary

InnateDB Protein

IDBP-813139.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GMFB

Protein Name

glia maturation factor, beta

Synonyms

GMF;

Species

Homo sapiens

Ensembl Protein

ENSP00000479543

InnateDB Gene

IDBG-7060 (GMFB)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	3 [view]
Protein-DNA	2 [view]
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0004860	protein kinase inhibitor activity
GO:0004871	signal transducer activity
GO:0008047	enzyme activator activity
GO:0008083	growth factor activity
GO:0071933	Arp2/3 complex binding

Biological Process

GO:0006468	protein phosphorylation
GO:0006469	negative regulation of protein kinase activity
GO:0007165	signal transduction
GO:0007399	nervous system development
GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation
GO:0043085	positive regulation of catalytic activity

Cellular Component

GO:0005622

intracellular

Protein Structure and Domains

PDB ID

InterPro

IPR002108 Actin-depolymerising factor homology domain
IPR011171 Glia maturation factor beta

PFAM

PF00241

PRINTS

PIRSF

PIRSF001788

SMART

SM00102

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

2764

UniGene

RefSeq

HUGO

HGNC:4373

OMIM

601713

CCDS

HPRD

IMGT

EMBL

AB001106 AK311753 CH471061 CR542113 M86492

GenPept

AAA58614 BAA19232 BAG34696 CAG46910 EAW80638