Version 5.4
Bos taurus Protein: MSRA
Summary
InnateDB Protein IDBP-680904.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MSRA
Protein Name Mitochondrial peptide methionine sulfoxide reductase
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000028825
InnateDB Gene IDBG-629499 (MSRA)
Protein Structure
UniProt Annotation
Function Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
Subcellular Localization Mitochondrion {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008113 peptide-methionine (S)-S-oxide reductase activity
GO:0016491 oxidoreductase activity
GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
Biological Process
GO:0006979 response to oxidative stress
GO:0030091 protein repair
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR002569 Peptide methionine sulphoxide reductase MsrA
PFAM PF01625
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P54149
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 281312
UniGene Bt.67939
RefSeq NP_776539
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102980 BT021044 U37150
GenPept AAC48539 AAI02981 AAX09061

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca