Version 5.4
Homo sapiens Protein: AUNIP
Summary
InnateDB Protein IDBP-592970.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AUNIP
Protein Name chromosome 1 open reading frame 135
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000443647
InnateDB Gene IDBG-94415 (AUNIP)
Protein Structure
UniProt Annotation
Function Required for the dynamic movement of AURKA at the centrosomes and spindle apparatus during the cell cycle. {ECO:0000269PubMed:20596670}.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269PubMed:20596670}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269PubMed:20596670}. Note=Localizes to the centrosome in interphase and to the spindle pole in metaphase.
Disease Associations
Tissue Specificity Expressed in heart, skeletal muscles, placenta and testis.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007051 spindle organization
Cellular Component
GO:0000922 spindle pole
GO:0005737 cytoplasm
GO:0005813 centrosome
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H7T9
PhosphoSite PhosphoSite-Q9H7T9
TrEMBL
UniProt Splice Variant
Entrez Gene 79000
UniGene Hs.725400
RefSeq NP_001274419
HUGO HGNC:28363
OMIM
CCDS CCDS72731
HPRD 08323
IMGT
EMBL AK024326 AK223419 AL020996 AL033528 BC000209 GQ844687
GenPept AAH00209 ACV90488 BAB14886 BAD97139 CAM12868

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca