InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HDAC2

Summary

InnateDB Protein

IDBP-480000.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HDAC2

Protein Name

histone deacetylase 2

Synonyms

HD2; RPD3; YAF1;

Species

Homo sapiens

Ensembl Protein

ENSP00000430008

InnateDB Gene

IDBG-95591 (HDAC2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 502 experimentally validated interaction(s) in this database.
They are also associated with 56 interaction(s) predicted by orthology.

Experimentally validated
Total	502 [view]
Protein-Protein	391 [view]
Protein-DNA	9 [view]
Protein-RNA	0
DNA-DNA	102 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	56 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004407	histone deacetylase activity
GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0046969	NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970	NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0097372	NAD-dependent histone deacetylase activity (H3-K18 specific)

Biological Process

GO:0006351	transcription, DNA-templated
GO:0016575	histone deacetylation
GO:0045087	innate immune response (InnateDB)
GO:0070932	histone H3 deacetylation
GO:0070933	histone H4 deacetylation