InnateDB Protein
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IDBP-295008.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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A2M
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Protein Name
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alpha-2-macroglobulin
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Synonyms
|
A2MD; CPAMD5; FWP007; S863-7;
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Species
|
Homo sapiens
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Ensembl Protein
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ENSP00000385710
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InnateDB Gene
|
IDBG-17623 (A2M)
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Protein Structure
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|
Function |
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 138 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
138
[view]
|
Protein-Protein |
138
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
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DNA-RNA |
0
|
|
|
|
Molecular Function |
Accession |
GO Term |
GO:0004866
|
endopeptidase inhibitor activity
|
|
Biological Process |
GO:0010951
|
negative regulation of endopeptidase activity
|
|
Cellular Component |
|
PDB ID |
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InterPro |
IPR002890
Alpha-2-macroglobulin, N-terminal
IPR008972
Cupredoxin
|
PFAM |
PF01835
|
PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
|
SwissProt |
|
PhosphoSite |
PhosphoSite-
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TrEMBL |
F8W7L3
|
UniProt Splice Variant |
|
Entrez Gene |
2
|
UniGene |
Hs.212838
|
RefSeq |
|
HUGO |
HGNC:7
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OMIM |
103950
|
CCDS |
|
HPRD |
00072
|
IMGT |
|
EMBL |
AC007436
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GenPept |
|
|
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