Version 5.4
Mus musculus Protein: Fam134b
Summary
InnateDB Protein IDBP-260264.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fam134b
Protein Name family with sequence similarity 134, member B
Synonyms 1810015C04Rik; AU015349;
Species Mus musculus
Ensembl Protein ENSMUSP00000106068
InnateDB Gene IDBG-131186 (Fam134b)
Protein Structure
UniProt Annotation
Function Required for long-term survival of nociceptive and autonomic ganglion neurons. {ECO:0000269PubMed:19838196}.
Subcellular Localization Golgi apparatus, cis-Golgi network membrane {ECO:0000269PubMed:19838196}; Single-pass membrane protein {ECO:0000269PubMed:19838196}.
Disease Associations
Tissue Specificity Predominantly expressed in sensory and autonomic ganglia has demonstrated by in situ hybridizations of embryonic day 14.5 mouse embryo sections. Detected specifically in organelle-like intracellular structures of the small and large neurons of dorsal root ganglia (DRG) and in Neuro-2a cells, a tumor cell line that is related to autonomic ganglion neurons (at protein level). {ECO:0000269PubMed:19838196}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0019233 sensory perception of pain
Cellular Component
GO:0005794 Golgi apparatus
GO:0005801 cis-Golgi network
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1913520
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8VE91
PhosphoSite PhosphoSite-Q8VE91
TrEMBL
UniProt Splice Variant
Entrez Gene 66270
UniGene Mm.473044
RefSeq NP_079735
MGI ID
MGI Symbol Fam134b
OMIM
CCDS CCDS37051
HPRD
IMGT
EMBL AK007506 AK015887 AK146972 AK167327 BC019494 BC054415
GenPept AAH19494 AAH54415 BAB25077 BAB30019 BAE27577 BAE39429

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca