Version 5.4
Homo sapiens Protein: ACAA1
Summary
InnateDB Protein IDBP-25585.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACAA1
Protein Name acetyl-CoA acyltransferase 1
Synonyms ACAA; PTHIO; THIO;
Species Homo sapiens
Ensembl Protein ENSP00000301810
InnateDB Gene IDBG-25581 (ACAA1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
Experimentally validated
Total 18 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0003988 acetyl-CoA C-acyltransferase activity
GO:0005515 protein binding
GO:0016401 palmitoyl-CoA oxidase activity
GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups
Biological Process
GO:0000038 very long-chain fatty acid metabolic process
GO:0006635 fatty acid beta-oxidation
GO:0008152 metabolic process
GO:0008206 bile acid metabolic process
GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase
GO:0033559 unsaturated fatty acid metabolic process
GO:0036109 alpha-linolenic acid metabolic process
GO:0044255 cellular lipid metabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005777 peroxisome
GO:0005782 peroxisomal matrix
GO:0016020 membrane
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID
InterPro IPR016039 Thiolase-like
IPR020616 Thiolase, N-terminal
IPR020617 Thiolase, C-terminal
PFAM PF00108
PF02803
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P09110
PhosphoSite PhosphoSite-P09110
TrEMBL
UniProt Splice Variant
Entrez Gene 30
UniGene Hs.643487
RefSeq NP_001123882
HUGO HGNC:82
OMIM 604054
CCDS CCDS46794
HPRD 06815
IMGT
EMBL AP006309 BC000635 BC011977 BC014474 CH471055 X12966 X14813 X65140 X65148
GenPept AAH00635 AAH11977 AAH14474 CAA31412 CAA32918 CAA46270 CAA46271 EAW64516

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca