Version 5.4
Mus musculus Protein: Safb2
Summary
InnateDB Protein IDBP-192433.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Safb2
Protein Name scaffold attachment factor B2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000074953
InnateDB Gene IDBG-192431 (Safb2)
Protein Structure
UniProt Annotation
Function Binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 26 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0042802 identical protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID MGI:2146808
InterPro IPR000504 RNA recognition motif domain
IPR003034 SAP domain
PFAM PF00076
PF02037
PRINTS
PIRSF
SMART SM00360
SM00513
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q80YR5
PhosphoSite PhosphoSite-Q80YR5
TrEMBL
UniProt Splice Variant
Entrez Gene 224902
UniGene Mm.482517
RefSeq NP_001025150
MGI ID
MGI Symbol Safb2
OMIM
CCDS CCDS28907
HPRD
IMGT
EMBL BC028827 BC050855
GenPept AAH28827 AAH50855

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca