Homo sapiens Gene: FAM134B
Summary
InnateDB Gene IDBG-13311.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FAM134B
Gene Name family with sequence similarity 134, member B
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000154153
Encoded Proteins
family with sequence similarity 134, member B
family with sequence similarity 134, member B
family with sequence similarity 134, member B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a cis-Golgi transmembrane protein that may be necessary for the long-term survival of nociceptive and autonomic ganglion neurons. Mutations in this gene are a cause of hereditary sensory and autonomic neuropathy type IIB (HSAN IIB), and this gene may also play a role in susceptibility to vascular dementia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:16473038-16617058
Strand Reverse strand
Band p15.1
Transcripts
ENST00000306320 ENSP00000304642
ENST00000399793 ENSP00000382691
ENST00000510362 ENSP00000425089
ENST00000509977
ENST00000506441
ENST00000509048
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0019233 sensory perception of pain
Cellular Component
GO:0005794 Golgi apparatus
GO:0005801 cis-Golgi network
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.481704
RefSeq NM_001034850 NM_019000 XM_005248312
HUGO
OMIM
CCDS CCDS43304 CCDS43305
HPRD 07879
IMGT
EMBL
GenPept
RNA Seq Atlas