InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: EEF2K

Summary

InnateDB Gene

IDBG-638351.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EEF2K

Gene Name

eukaryotic elongation factor 2 kinase

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000017662

Encoded Proteins

IDBP-690415

eukaryotic elongation factor-2 kinase

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000103319:
This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 25:20115008-20165902

Strand

Forward strand

Band

Transcripts

ENSBTAT00000023487

ENSBTAP00000023487

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.

Predicted by orthology
Total	15 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004674	protein serine/threonine kinase activity
GO:0004686	elongation factor-2 kinase activity
GO:0005509	calcium ion binding
GO:0005516	calmodulin binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups