Version 5.4
Bos taurus Gene: DNAH5
Summary
InnateDB Gene IDBG-631395.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DNAH5
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000021972
Encoded Proteins
IDBP-683050
dynein, axonemal, heavy chain 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000039139:
This gene encodes a dynein protein, which is part of a microtubule-associated motor protein complex consisting of heavy, light, and intermediate chains. This protein is an axonemal heavy chain dynein. It functions as a force-generating protein with ATPase activity, whereby the release of ADP is thought to produce the force-producing power stroke. Mutations in this gene cause primary ciliary dyskinesia type 3, as well as Kartagener syndrome, which are both diseases due to ciliary defects. [provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:59285274-59560606
Strand Forward strand
Band
Transcripts
ENSBTAT00000061278 ENSBTAP00000053219
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0017111 nucleoside-triphosphatase activity
Biological Process
GO:0003341 cilium movement
GO:0006200 ATP catabolic process
GO:0007018 microtubule-based movement
GO:0008152 metabolic process
GO:0021670 lateral ventricle development
GO:0070986 left/right axis specification
Cellular Component
GO:0005858 axonemal dynein complex
GO:0005930 axoneme
GO:0030286 dynein complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000039139
View Gene Order
ENSMUSG00000022262
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa05016
Huntington's disease pathway
mmu05016
Huntington's disease pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BMG2
UniProt Splice Variant
Entrez Gene 101909877
UniGene Bt.25491 Bt.65326
RefSeq XM_002696448 XM_003583703 XM_003583704 XM_005200282 XM_005200463
HUGO HGNC:2950
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02051129 DAAA02051130 DAAA02051131 DAAA02051132
GenPept
RNA Seq Atlas 100298754 101909267 101909877

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca