Version 5.4
Mus musculus Gene: Pkp3
Summary
InnateDB Gene IDBG-211965.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pkp3
Gene Name plakophilin 3
Synonyms 2310056L12Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000054065
Encoded Proteins
IDBP-211967
plakophilin 3
IDBP-269595
plakophilin 3
IDBP-541108
plakophilin 3
IDBP-535984
plakophilin 3
IDBP-542057
plakophilin 3
IDBP-542518
plakophilin 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184363:
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:141078218-141090510
Strand Forward strand
Band F5
Transcripts
ENSMUST00000066873 ENSMUSP00000069961
ENSMUST00000106039 ENSMUSP00000101654
ENSMUST00000159375 ENSMUSP00000124572
ENSMUST00000163041 ENSMUSP00000124434
ENSMUST00000160869 ENSMUSP00000124013
ENSMUST00000160615
ENSMUST00000160403
ENSMUST00000159253
ENSMUST00000161142
ENSMUST00000160356 ENSMUSP00000123783
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0050839 cell adhesion molecule binding
Biological Process
GO:0002159 desmosome assembly
GO:0016337 single organismal cell-cell adhesion
GO:0090002 establishment of protein localization to plasma membrane
Cellular Component
GO:0005634 nucleus
GO:0005886 plasma membrane
GO:0005914 spot adherens junction
GO:0030057 desmosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000184363
View Gene Order
ENSBTAG00000048098
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.350037
RefSeq NM_001162924 NM_019762 XM_006536215
OMIM
CCDS CCDS21999 CCDS52437
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca