|Mus musculus Gene: Usp25|
|Last Modified||2014-10-13 [Report errors or provide feedback]|
|Gene Name||ubiquitin specific peptidase 25|
ubiquitin specific peptidase 25
|Useful resources||Stemformatics EHFPI ImmGen|
Usp25 physically associates with Traf3 and Traf6 after infection by RNA or DNA viruses and promotes innate antiviral responses by protecting virus-induced proteasome-dependent or independent degradation of Traf3 and Traf6.
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000155313:
Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response. Ubiquitin is released from degraded proteins by disassembly of the polyubiquitin chains, which is mediated by ubiquitin-specific proteases (USPs), such as USP25 (Valero et al., 1999 [PubMed 10644437]).[supplied by OMIM, Mar 2008]
|Genomic Location||Chromosome 16:77014069-77116779|
|Number of Interactions||
This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
|TrEMBL||Q8BR08 Q8CBA4 Q9CSW6|
|UniProt Splice Variant|
|EMBL||AF170563 AK011798 AK036456 AK045966 BC048171 BC063059|
|GenPept||AAF32264 AAH48171 AAH63059 BAB27849 BAC29438 BAC32550|
|RNA Seq Atlas||30940|